Practical use of the Lexis machinery for multistate models

• Reports in .pdf (from Sweave) format that details practical analyses of follow-up studies that have been published in the medical literature (papers also in .pdf format):
  • Mortality among Australian Diabetes Patients
    Published paper: Impact of age at diagnosis and duration of type 2 diabetes on mortality in Australia 1997-2011
    Electronic Supplementary material is here.
  • Steno 2 study 21 year follow-up - end of 2014
    Published paper: Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial
    Electronic Supplementary material with all the fun stuff here.
  • Analysis plan, data requirements and analysis of HH events in DK
    Published paper: Incidence Trends and Predictors of Hospitalization for Hypoglycemia in 17,230 Adult Patients with Type 1 Diabetes: A Danish Register Linkage Cohort Study
    Supplementary material here.
  • Diabetes and Tuberculosis in Denmark
    Published paper: Diabetes-related tuberculosis in Denmark: effect of ethnicity, diabetes duration and year of diagnosis
  • Cancer in T1D patients: Protocol & Data analysis
    Published paper: Cancer incidence in persons with type 1 diabetes: a five-country study of 9,000 cancers in type 1 diabetic individuals
  • Diabetes and amputation incidence in Fyn county, Denmark
    Published paper: Substantial reduction in the number of amputations among patients with diabetes: a cohort study over 16 years
  • Mortality and morbidity among T2D DN patients
    Published paper: Improved Survival and Renal Prognosis of Patients With Type 2 Diabetes and Nephropathy with Improved Control of Risk Factors
  • Mortality and morbidity among T1D DN patients
    Published paper: Improved prognosis of diabetic nephropathy in type 1 diabetes
  • The Epidemiology of Diabetes and Cancer
    Published paper: The Epidemiology of Diabetes and Cancer
    Unpublished report: Demographic changes in the burden of Diabetes and Cancer in Denmark 1995-2012
• Ad hoc demo reports:
  • Multistate example from SiM paper by Crowther and Lambert.
    The corresponding R-code.
  • Multistate models in Epi: The DLI example from JSS: the etm package by Allignol et al..
    The corresponding R-code.
  • Rates and (competing) risks: Example calculations using Danish cause of death data.
• Statistical background papers:
  • Plummer & Carstensen: Lexis: An R Class for Epidemiological Studies with Long-term Follow-up.
  • Carstensen & Plummer: Using Lexis Objects for Multi-state Models in R.
  • Iacobelli & Carstensen: Multiple timescales in multi-state models
• Modern Demographic Methods in Epidemiology